TAK1-IN-5 (Compound 26) is an inhibitor of the transforming growth factor-beta activated kinase (TAK1) with an IC50 value of 55 nM. TAK1-IN-5 can inhibit the growth of MPC-11 and H929 cells with a GI50 lower than 30 nM. TAK1-IN-5 can be used in the study of multiple myeloma [1].
Molekulargewicht:
388.47
Formel:
C22H24N6O
Target-Kategorie:
MAP3K
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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