Elobixibat (A 3309, AZD 7806) hydrate is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat hydrate can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat hydrate can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly[1][2][3].
Molekulargewicht:
713.90
Reinheit:
99.44
CAS Nummer:
[1633824-78-8]
Formel:
C36H47N3O8S2
Target-Kategorie:
Apical Sodium-Dependent Bile Acid Transporter
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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