GluN2B-NMDAR antagonist-2 (compound S-58) is a potent, selective and cross the blood-brain barrier NMDAR-GluN2B antagonist with an IC50 value of 74.01, nM. GluN2B-NMDAR antagonist-2 shows mild cytotoxicity. GluN2B-NMDAR antagonist-2 decreases the cerebral infarction rates and neurologic deficit scores. GluN2B-NMDAR antagonist-2 has the potential for the research of stroke[1].
Molekulargewicht:
474.38
Formel:
C24H25Cl2N3O3
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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