BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state [1].
Molekulargewicht:
729.74
Reinheit:
99.90
CAS Nummer:
[2893809-51-1]
Formel:
C35H33F6N7O2S
Target-Kategorie:
Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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