CA IX/VEGFR-2-IN-2 (compound 5e) is a dual-targeted inhibitor. CA IX/VEGFR-2-IN-2 shows strong inhibitory effects on both CA IX (Ki=3.1 µM) and VEGFR-2 (IC50=32.1 nM). CA IX/VEGFR-2-IN-2 can be used for the study of pancreatic (PANC1), breast cancer (MCF7) and prostate cancer (PC3) [1].
Molekulargewicht:
423.46
Formel:
C22H18FN3O3S
Target-Kategorie:
Bcl-2 Family,Carbonic Anhydrase,Caspase,Cytochrome P450,MDM-2/p53,Reactive Oxygen Species (ROS),VEGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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