MAO-B-IN-33, CAS [[2286257-25-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-158732
Hersteller Artikelnummer:
HY-158732
Alternativnummer:
MCE-HY-158732-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
MAO-B-IN-33 (compound C3) is a potent, reversible and selective monoamine oxidase-B (MAO-B) inhibitor with an IC50 of 0.021 µM and 26.805 µM for MAO-B and MAO-A, respectively. The selectivity of MAO-B-IN-33 is attributed to the steric clash arising from the residue differences between Phe208 (MAO-A) and Ile199 (MAO-B). MAO-B-IN-33 inhibits cerebral MAO-B activity and alleviates MPTP (HY-15608)-induced dopaminergic neuronal loss in the mouse. MAO-B-IN-33 has the potential for Parkinsons disease research[1].
Molekulargewicht:
314.35
CAS Nummer:
[2286257-25-6]
Formel:
C18H19FN2O2
Target-Kategorie:
Monoamine Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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