GK241 (compound 31a-c) is a 2-oxoamide-based compound that has inhibitory activity against human and mouse group IIA secretory phospholipase A2 (GIIA sPLA2) (IC50 of 143 nM and 68 nM, respectively), and its inhibitory mechanism was studied by molecular dynamics simulation.
Molekulargewicht:
369.54
CAS Nummer:
[1899930-93-8]
Formel:
C21H39NO4
Target-Kategorie:
Phospholipase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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