Voxtalisib (Standard) is the analytical standard of Voxtalisib. This product is intended for research and analytical applications. Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110alpha, p110beta, p110gamma and p110delta, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.
Molekulargewicht:
270.29
CAS Nummer:
[934493-76-2]
Formel:
C13H14N6O
Target-Kategorie:
mTOR,PI3K,Reference Standards
Anwendungsbeschreibung:
Reference Standards
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