CA IX-IN-2, CAS [[3009842-92-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: CA IX-IN-2, CAS [[3009842-92-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-159122
• Hersteller Artikelnummer: HY-159122
• Alternativnummer: MCE-HY-159122-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CA IX-IN-2 (Compound 9o) is an inhibitor for carbonic anhydrase (CA), that inhibits CA IX, CA XII and CA II with an IC50 of 5.6, 7.4 and 430 nM, respectively. CA IX-IN-2 inhibits the proliferation of cancer cell HCT-116, SW480, MDA-MB 231 and MCF-7, with IC50s of 14.63-29.33 µM. CA IX-IN-2 intercalates DNA, arrests cell cycle at G1/S phase, and induces apoptosis in MDA-MB-231. CA IX-IN-2 affects the mitochondrial membrane potential (MMP), increases the intracellular ROS levels, causes mitochondrial damage, and inhibits the cell migration of MDA-MB-231. CA IX-IN-2 exhibits antitumor efficacy in mouse models[1].

Produkteigenschaften

• Molekulargewicht: 592.71
• CAS Nummer: [3009842-92-3]
• Formel: C30H36N6O5S
• Target-Kategorie: Apoptosis,Carbonic Anhydrase,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound