HRS-4642, CAS [[2836263-09-1]]

Produktübersicht

• Artikelname: HRS-4642, CAS [[2836263-09-1]]
• Artikelnummer: MCE-HY-159127
• Hersteller Artikelnummer: HY-159127
• Alternativnummer: MCE-HY-159127-10MMX1ML,MCE-HY-159127-5MG,MCE-HY-159127-10MG,MCE-HY-159127-100MG,MCE-HY-159127-50MG,MCE-HY-159127-1MG,MCE-HY-159127-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HRS-4642 is a high affinity, selective, long-acting, and non-covalent KRASG12D inhibitor with a Kd value of 0.083 nM. HRS-4642 inhibits the binding of KRASG12D to SOS1 or RAF1, thereby blocking the downstream MEK-ERK signaling pathway. HRS-4642 promotes Apoptosis. HRS-4642 alone or combined with Carfilzomib (HY-10455) effectively shapes the tumor microenvironment. HRS-4642 has an anti-cancer effect on pancreatic and colorectal cancers carrying the KRASG12D mutation[1][2][3].

Produkteigenschaften

• Molekulargewicht: 632.68
• Reinheit: 98.38
• CAS Nummer: [2836263-09-1]
• Formel: C34H35F3N6O3
• Target-Kategorie: Apoptosis,MEK,PERK,Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1