PPARalpha agonist 4 (compound BH400) is a PPARalpha agonist (EC50= 1.2 µM). PPARalpha agonist 4 also inhibits STING (IC50: 8.1 µM). PPARalpha agonist 4 reduces the CoCl2-induced production of ROS and LPS-induced secretion of IL-6. The PPARalpha agonist 4 restores the decreased expression of PCG1alpha induced by LPS[1].
Molekulargewicht:
337.34
Formel:
C20H16FNO3
Target-Kategorie:
PPAR,Reactive Oxygen Species (ROS),STING
Anwendungsbeschreibung:
MCE Product type: Reference compound
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