HRX-0233, CAS [[2409140-12-9]]

Produktübersicht

• Artikelname: HRX-0233, CAS [[2409140-12-9]]
• Artikelnummer: MCE-HY-159190
• Hersteller Artikelnummer: HY-159190
• Alternativnummer: MCE-HY-159190-50MG,MCE-HY-159190-25MG,MCE-HY-159190-10MG,MCE-HY-159190-100MG,MCE-HY-159190-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HRX-0233 is a small-molecule MAP2K4 inhibitor. HRX-0233 results in strong tumor shrinkage without any apparent toxicity in H358 KRASG12C-mutant non-small cell lung cancers (NSCLC) in vivo. HRX-0233 efficiently prevents feedback activation of receptor tyrosine kinases (RTKs) upon monotherapy KRAS inhibitor Sotorasib (HY-114277) and causes a more sustained and complete inhibition of MAPK signaling. HRX-0233 is promising for research of AR-negative prostate cancer, lung and colon cancers[1][2].

Produkteigenschaften

• Molekulargewicht: 497.52
• Reinheit: 98.92
• CAS Nummer: [2409140-12-9]
• Formel: C24H21F2N5O3S
• Target-Kategorie: MAPKAPK2 (MK2)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound