Hsp110/sGC-modulator-1 (compound 17i), an orally active Hsp110/sGC dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression[1].
Molekulargewicht:
490.86
Reinheit:
99.58
Formel:
C24H18ClF3N2O4
Target-Kategorie:
Guanylate Cyclase,HSP
Anwendungsbeschreibung:
Reference compound
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