Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity[1][2].
Molekulargewicht:
345.36
Reinheit:
99.99
CAS Nummer:
[1313725-88-0]
Formel:
C17H15N9
Target-Kategorie:
c-Met/HGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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