Ulacamten, CAS [[2830607-59-3]]

Produktübersicht

• Artikelname: Ulacamten, CAS [[2830607-59-3]]
• Artikelnummer: MCE-HY-159821
• Hersteller Artikelnummer: HY-159821
• Alternativnummer: MCE-HY-159821-50MG,MCE-HY-159821-100MG,MCE-HY-159821-5MG,MCE-HY-159821-10MMX1ML,MCE-HY-159821-1G,MCE-HY-159821-10MG,MCE-HY-159821-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CK-4021586, CK-586

Produktbeschreibung

Ulacamten (CK-4021586, CK-586) is an orally active cardiac myosin inhibitor and an inhibitor of the double-headed cardiac heavy meromyosin (HMM)ATPase (excluding single-headed myosin subfragment-1), with an EC50 of 2.9 µM. Ulacamten regulates cardiac myosin, reduces excessive myocardial contractility, and alleviates left ventricular outflow tract obstruction. Ulacamten increases the left ventricular short-axis systolic internal diameter, inhibits dobutamine-induced exacerbation of obstruction, and exerts only a mild reducing effect on left ventricular systolic function. Ulacamten also inhibits the fractional shortening of the short axis without altering calcium transients. Ulacamten shows good safety and tolerability in purpose-bred cats with naturally occurring obstructive hypertrophic cardiomyopathy[1][2].

Produkteigenschaften

• Molekulargewicht: 405.44
• Reinheit: 99.22
• CAS Nummer: [2830607-59-3]
• Formel: C21H25F2N3O3
• Target-Kategorie: Myosin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound