PTK7/beta-catenin-IN-2 (compound 04967) is an inhibitor of PTK7/beta-catenin. It inhibits the binding of PTK7 to beta-catenin (IC50: 5.6 µM), thereby inhibiting the signaling of the Wnt/beta-catenin pathway. PTK7/beta-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/beta-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC50 of 157.1 µM[1].
Molekulargewicht:
565.54
Reinheit:
96.96
CAS Nummer:
[902434-29-1]
Formel:
C30H34Cl2N6O
Target-Kategorie:
Wnt,beta-catenin
Anwendungsbeschreibung:
Reference compound
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