ELOVL6-IN-5, CAS [[1135000-36-0]]

Artikelnummer: MCE-HY-160912
Artikelname: ELOVL6-IN-5, CAS [[1135000-36-0]]
Artikelnummer: MCE-HY-160912
Hersteller Artikelnummer: HY-160912
Alternativnummer: MCE-HY-160912-5MG,MCE-HY-160912-25MG,MCE-HY-160912-50MG,MCE-HY-160912-100MG,MCE-HY-160912-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
ELOVL6-IN-5 is an orally active and selective elongase enzyme of long-chain fatty acid family 6 (ELOVL6) inhibitor with IC50 values of 85 nM and 38 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-5 shows >60-fold selectivity over other ELOVL family enzymes (ELOVL1, 2, 3, 5) and no effect on other lipid synthesis enzymes like ACC1, ACC2. ELOVL6-IN-5 reduces hepatic fatty acid composition ratio of C18 to C16 in diet-induced obesity (DIO) and KKAy mice. ELOVL6 inhibition by ELOVL6-IN-5 does not improve insulin resistance. ELOVL6-IN-5 can be used for the research of metabolic disease[1].
Molekulargewicht: 439.45
Reinheit: 95.12
CAS Nummer: [1135000-36-0]
Formel: C20H20F3N3O3S
Target-Kategorie: ELOVL
Anwendungsbeschreibung: MCE Product type: Reference compound