Spire2/FMN2 PPI-IN-1 (Compound 13) dihydrochloride is a selective inhibitory fragment targeting the Spire2-FMN2 interaction, with an IC50 of 62 µM. Spire2/FMN2 PPI-IN-1 dihydrochloride has affinity for KIND2, with a Kd of 87.7 µM, and does not inhibit KIND1. Spire2/FMN2 PPI-IN-1 dihydrochloride can be used for the development of chemical probes for the Spire2-FMN2 interaction[1].
Molekulargewicht:
278.15
Reinheit:
98.99
Formel:
C11H14Cl2FN3
Target-Kategorie:
Arp2/3 Complex
Anwendungsbeschreibung:
MCE Product type: Reference compound
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