BMS-214662 is a farnesyl transferase inhibitor. BMS-214662 can effectively block the localization and function of Ras protein in the cell membrane by inhibiting the pro-group modification of Ras protein, thereby exerting anti-tumor activity. BMS-214662 has an IC50 value of 1.3 nM for H-Ras and 8.4 nM for K-Ras. BMS-214662 can be used to study Ras-related tumor diseases[1][2].
Molekulargewicht:
489.61
Reinheit:
99.86
CAS Nummer:
[195987-41-8]
Formel:
C25H23N5O2S2
Target-Kategorie:
Farnesyl Transferase,Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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