BMS-214662 hydrochloride is an inhibitor of farnesyltransferase (Farnesyl Transferase). BMS-214662 hydrochloride can effectively block the localization and function of Ras proteins on the cell membrane by inhibiting the prenylation modification of Ras proteins, thereby exerting anti-tumor activity. The IC50 value of BMS-214662 hydrochloride for H-Ras is 1.3 nM, and for K-Ras it is 8.4 nM. BMS-214662 hydrochloride can be used in the research of tumor diseases related to Ras[1][2].
Molekulargewicht:
526.07
Reinheit:
98.54
CAS Nummer:
[195981-08-9]
Formel:
C25H24ClN5O2S2
Target-Kategorie:
Farnesyl Transferase,Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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