PROTAC KRAS G12D degrader 2 is a peptidomimetic PROTAC specifically targeting the dimeric SARS-CoV-2 3CLPro protein. PROTAC KRAS G12D degrader 2 inhibits SARS-CoV-2 3CLPro with an IC50 of 21.2 µM. PROTAC KRAS G12D degrader 2 specifically binds to the active site of SARS-CoV-2 3CLPro. PROTAC KRAS G12D degrader 2 reduces protein levels of SARS-CoV-2 3CLPro without affecting cell viability. PROTAC KRAS G12D degrader 2 can be used for the study of viral infections in Coronavirus genera[1].
Molekulargewicht:
884.99
Reinheit:
98.59
Formel:
C46H57FN8O9
Target-Kategorie:
PROTACs,SARS-CoV,Virus Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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