Antibiofilm agent-5 (compound 6c) is a multitargeting antibacterial agent with potent antibiofilm activity. Antibiofilm agent-5 could induce metabolic dysfunction by deactivating lactate dehydrogenase and promote the accumulation of reactive oxygen species to decrease the reduced glutathione and ultimately cause oxidative damage in bacteria. Antibiofilm agent-5 can be used for the research of refractory biofilm-intensified bacterial infections[1].
Molekulargewicht:
608.11
Formel:
C25H34ClN9O5S
Target-Kategorie:
Bacterial,Lactate Dehydrogenase,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
Reference compound
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