CFTR corrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector (EC50=3.14 µM). CFTR corrector 13 enhances the function of CFTR channels, especially when used in combination with Lumacaftor (HY-13262), it can produce a dose-dependent increase in CFTR function. CFTR corrector 13 can be used in the study of cystic fibrosis (CF) and other CFTR-related diseases[1].
Molekulargewicht:
537.03
Formel:
C27H25ClN4O4S
Target-Kategorie:
CFTR
Anwendungsbeschreibung:
Reference compound
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