GPX4 activator 2 is a GPX4 activator with a Ka value of 0.426 µM for human GPX4. GPX4 activator 2 reduces lipid hydroperoxide levels, prevents lipid peroxide accumulation, and inhibits ferroptosis. GPX4 activator 2 rescues cell death induced by Erastin (HY-15763). GPX4 activator 2 exerts cardioprotective effects in a mouse model of doxorubicin (HY-15142A)-induced myocardial injury[1].
Molekulargewicht:
414.52
Reinheit:
99.23
CAS Nummer:
[950365-31-8]
Formel:
C20H26N6O2S
Target-Kategorie:
Ferroptosis,Glutathione Peroxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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