XSJ05 is a camptothecin (CPT) derivative that can inhibit topoisomerase I (Topo I) to exert anti-cancer activity. XSJ05 can trigger DNA double-strand breaks, leading to DNA damage. XSJ05 can inhibit the growth of colorectal cancer (CRC), arrest the cell cycle in G2/M phase, and induce apoptosis[1].
Molekulargewicht:
539.60
CAS Nummer:
[1461652-87-8]
Formel:
C29H25N5O4S
Target-Kategorie:
Apoptosis,Topoisomerase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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