Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research[1].
Molekulargewicht:
570.72
Formel:
C38H38N2O3
Target-Kategorie:
Cytochrome P450
Anwendungsbeschreibung:
Reference compound
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