Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma[1][2][3].
Molekulargewicht:
383.16
Reinheit:
98
CAS Nummer:
[132682-98-5]
Formel:
C10H21Cl2N2O7P
Target-Kategorie:
Apoptosis,Bcl-2 Family,Caspase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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