CSF1R-IN-22, CAS [[2760585-35-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-162415
Hersteller Artikelnummer:
HY-162415
Alternativnummer:
MCE-HY-162415-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
CSF1R-IN-22 (Compound C19) is an orally effective CSF-1R selective inhibitor (IC50+ T cell infiltration. CSF1R-IN-22 boosts anti-tumor immune responses of anti-PD-1, and induces apoptosis in tumor cells. CSF1R-IN-22 can effectively reprogram M2-like TAMs (tumor-associated macrophages) to the M1 phenotype and reshape the TME by inducing the recruitment of CD8+ T cells into tumors and reducing the infiltration of immunosuppressive Tregs and MDSCs[1].
Molekulargewicht:
392.41
CAS Nummer:
[2760585-35-9]
Formel:
C20H20N6O3
Target-Kategorie:
Apoptosis,c-Fms
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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