SQA1, a squaramide (SQA) derivative, is a CCR6 antagonist with a Kd of 250 nM. SQA1 is also a CXCR2 inhibitor. The intracellular pocket occupied by SQA1 overlaps with the G protein binding site and stabilizes the closed conformation of the intracellular pocket[1].
Molekulargewicht:
426.47
CAS Nummer:
[1255915-27-5]
Formel:
C22H26N4O5
Target-Kategorie:
CCR,CXCR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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