NRL-1049, CAS [[1973494-16-4]]

Artikelnummer: MCE-HY-162596
Artikelname: NRL-1049, CAS [[1973494-16-4]]
Artikelnummer: MCE-HY-162596
Hersteller Artikelnummer: HY-162596
Alternativnummer: MCE-HY-162596-25MG,MCE-HY-162596-1MG,MCE-HY-162596-5MG,MCE-HY-162596-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: BA-1049 (free base)
NRL-1049 (BA-1049 (free base)) is an orally available and selective ROCK2 inhibitor with IC50 values of 0.59 µM for ROCK2 and 26 µM for ROCK1, respectively. NRL-1049 modulates ROCK signaling, preserves blood-brain barrier integrity, reduces edema, seizures and hemorrhage, and alleviates cerebral cavernous malformation lesion burden. NRL-1049 can be used for the study of acute brain injury, ischemic stroke, and cerebral cavernous malformations[1][2].
Molekulargewicht: 319.42
Reinheit: 99.96
CAS Nummer: [1973494-16-4]
Formel: C16H21N3O2S
Target-Kategorie: ROCK
Anwendungsbeschreibung: MCE Product type: Reference compound