BRD5075 is a selective GPR65 activator. BRD5075 enhances GPR65 activity under acidic conditions, promotes Galphas-dependent signaling pathways, including cAMP production and G protein recruitment. BRD5075 regulates the cytokine and chemokine expression network in dendritic cells, and inhibits the expression of pro-inflammatory cytokines and chemokines in a GPR65-dependent manner. BRD5075 is applicable to research related to inflammatory bowel disease[1].
Molekulargewicht:
417.46
Reinheit:
98.08
Formel:
C23H23N5O3
Target-Kategorie:
GPR65
Anwendungsbeschreibung:
MCE Product type: Reference compound
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