NB512 (compound 39a) is a dual inhibitor for BET and HDAC, which exhibits a efficient binding affinity with BRD4 bromodomains and HDAC1/2, with EC50s of 100-400 nM. NB512 exhibits an anti-proliferative activity towards cancer cells PaTu8988T and NMC[1].
Molekulargewicht:
435.48
Formel:
C26H21N5O2
Target-Kategorie:
Epigenetic Reader Domain,HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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