AR/AR-V7-IN-1 (Compound 20i) is an AR/ARV7 inhibitor (IC50 = 172.85 nM). AR/AR-V7-IN-1 potently inhibits cell growth with IC50 values of 4.87 and 2.07 µM in the LNCaP and 22RV1 cell lines, respectively. AR/AR-V7-IN-1 exhibits effective tumor growth inhibition in the 22RV1 xenograft study. AR/AR-V7-IN-1 can be used for the research of prostate cancer[1].
Molekulargewicht:
660.22
CAS Nummer:
[2964558-54-9]
Formel:
C36H43ClFN7O2
Target-Kategorie:
Androgen Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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