JYQ-164 is a small molecule inhibitor of Parkinsons disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinsons disease and cancer research[1].
Molekulargewicht:
530.62
Reinheit:
99.43
Formel:
C23H26N6O5S2
Target-Kategorie:
PINK1/Parkin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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