Omtriptolide (sodium), CAS [[195883-09-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-16362
Hersteller Artikelnummer:
HY-16362
Alternativnummer:
MCE-HY-16362-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
PG 490-88Na
Omtriptolide sodium (PG490-88Na) is a derivative of Triptolide (HY-32735). Omtriptolide sodium exhibits significant immunosuppressive, anti-fibrotic and anti-inflammatory properties. The mechanism of action of Omtriptolide sodium is diverse, including inhibiting T cell activation and proliferation, inducing T cell apoptosis (apoptosis), blocking fibroblast maturation/proliferation, inhibiting TGF-beta mRNA expression, and suppressing pro-inflammatory cytokines (such as IL-2, IFN-gamma, TNF-alpha) by blocking transcription factors such as NF-kappaB. Omtriptolide sodium can be used for research on obstructive airway diseases, pulmonary fibrosis and graft-versus-host disease[1][2][3][4].
