Fraxinellone analog 1 (compound 2) is a potent and rapid activator of the Nrf2 mediated antioxidant defense system, which protects against glutamate-mediated excitotoxicity and induces the expression of antioxidant genes Gpx4, Sod1, and Nqo1. Fraxinellone analog 1 has neuroprotective effects and regulatory effects against oxidative stress and inflammation, and can be used in the study of neurodegenerative diseases[1].
Molekulargewicht:
208.25
Formel:
C12H16O3
Target-Kategorie:
Keap1-Nrf2
Anwendungsbeschreibung:
Reference compound
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