CDK2 degrader 1 (Compound 3) is a selective CDK2 molecular glue degrader with a Dmax (CDK2) of > 80% and a Ki (CRBN) > 1 µM. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2. CDK2 degrader 1 is used in the research of a wide range of cancers[1].
Molekulargewicht:
447.47
Reinheit:
99.74
CAS Nummer:
[3036604-59-5]
Formel:
C23H27F2N3O4
Target-Kategorie:
CDK,Molecular Glues
Anwendungsbeschreibung:
MCE Product type: Reference compound
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