BHA536 is an orally active selective inhibitor for PKCalpha/beta and NF-kB signaling pathway. BHA536 inhibits the proliferation of CD79-mutated ABC DLBCL cell, arrests cell cycle at G1 phase, and induces apoptosis in TMD8 cell. BHA536 exhibits antitumor efficacy in mice[1].
Molekulargewicht:
548.03
CAS Nummer:
[919992-85-1]
Formel:
C30H30ClN3O5
Target-Kategorie:
Apoptosis,NF-kappaB,PKC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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