CD38-IN-5 (compound 1) is a CD38 inhibitor that selectively inhibits CD38 hydrolase with an IC50 of 4.0 µM. CD38-IN-5 does not inhibits CD38 cyclase. CD38-IN-5 is highly effective at promoting NK cell-mediated tumor toxicity. CD38-IN-5 increases NADH+ and IFNgamma levels in activated PBMCs. CD38-IN-5 can be used for the study of cancer[1].
Molekulargewicht:
309.41
CAS Nummer:
[314039-40-2]
Formel:
C18H23N5
Target-Kategorie:
CD38
Anwendungsbeschreibung:
MCE Product type: Reference compound
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