AGN-190851 is a potent and selective agonist of alpha2-adrenergic receptor (alpha2 adrenoceptor). AGN-190851 induces dose-dependent water diuresis in rats, and inhibits vasopressin V2 receptor in a species-dependent manner in vitro, thereby suppressing cAMP production. AGN-190851 enhances the contraction of porcine myometrium. AGN 190851 can be used in studies on renal diuretic mechanisms, pharmacology of alpha2-adrenergic receptor subtypes, and parturition[1][2].
Molekulargewicht:
296.17
CAS Nummer:
[134892-42-5]
Formel:
C11H14BrN5
Target-Kategorie:
Adrenergic Receptor,Vasopressin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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