ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. ML337 possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile[1]. ML337 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
353.39
Reinheit:
99.13
CAS Nummer:
[1443118-44-2]
Formel:
C21H20FNO3
Target-Kategorie:
mGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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