Z-VAD-FMK, CAS [[161401-82-7]]

Produktübersicht

• Artikelname: Z-VAD-FMK, CAS [[161401-82-7]]
• Artikelnummer: MCE-HY-16658B
• Hersteller Artikelnummer: HY-16658B
• Alternativnummer: MCE-HY-16658B-10MMX1ML,MCE-HY-16658B-10MG,MCE-HY-16658B-100MG,MCE-HY-16658B-25MG,MCE-HY-16658B-5MG,MCE-HY-16658B-1MG,MCE-HY-16658B-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Z-VAD(OH)-FMK

Produktbeschreibung

Z-VAD-FMK is a pan-caspase inhibitor and also an ICE-like protease inhibitor, which inhibits apoptosis by preventing the processing of CPP32 to its active form. Z-VAD-FMK sensitivity varies primarily due to differential expression of receptor-interacting protein 1 (RIP1). Z-VAD-FMK limits the cryopreservation-induced apoptosis by reducing caspase-3 activity of in vitro produced bovine embryos. Z-VAD-FMK is immunosuppressive in vitro and inhibits T cell proliferation without blocking the processing of caspase-8 and caspase-3. Z-VAD-FMK leads to a decrease in intracellular glutathione (GSH) with a concomitant increase in reactive oxygen species (ROS) levels in activated T cells. Z-VAD-FMK is due to oxidative stress via the depletion of GSH. Z-VAD-FMK can be used for the study of acute pancreatitis[1][2][3][4][5][6][7].

Produkteigenschaften

• Molekulargewicht: 453.46
• Reinheit: 99.78
• CAS Nummer: [161401-82-7]
• Formel: C21H28FN3O7
• Target-Kategorie: Apoptosis,Caspase,Glutathione Peroxidase,Reactive Oxygen Species (ROS),RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound