NPD6433 is a triazenyl indole with broad-spectrum activity against all screening fungal strains. NPD6433 targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH-oxidation activity and arresting essential fatty acid biosynthesis[1].
Molekulargewicht:
391.42
Formel:
C21H21N5O3
Target-Kategorie:
Fatty Acid Synthase (FASN),Fungal
Anwendungsbeschreibung:
MCE Product type: Reference compound
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