NOD1/-IN-1 (Compound 2) is a potent RIPK2 inhibitor with an IC50 value of 0.65 nM determined by ADP-Glo assays. NOD1/-IN-1 selectively inhibits the NOD1 pathway (with an IC50 of 33 nM for NOD1), blocking the production of pro-inflammatory cytokines and thereby reducing inflammation. NOD1/-IN-1 is applicable for research in the field of colitis[1].
Molekulargewicht:
331.75
CAS Nummer:
[687627-78-7]
Formel:
C16H14ClN3O3
Target-Kategorie:
NOD-like Receptor (NLR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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