PROTAC TBL1X degrader-1 (Compound TD11) is a PROTAC degrader for Transducin beta-like protein 1 X-linked (TBL1X), and exhibits cytotoxicity in lymphoma cell Riva, Pfeiffer and Granta-519 with IC50 of 0.795, 0.397 and 0.522 µM, respectively. (Pink: ligand for target protein: TBL1X ligand 1 (HY-168191), Black: linker (HY-168193), Blue: ligand for E3 ligase: Thalidomide 4-fluoride (HY-41547))[1]
Molekulargewicht:
1001.18
Formel:
C49H60N8O11S2
Target-Kategorie:
PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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