TrxR/EGFR-IN-1, CAS [[3038386-42-1]]

Produktübersicht

• Artikelname: TrxR/EGFR-IN-1, CAS [[3038386-42-1]]
• Artikelnummer: MCE-HY-168492
• Hersteller Artikelnummer: HY-168492
• Alternativnummer: MCE-HY-168492-10MG,MCE-HY-168492-5MG,MCE-HY-168492-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TrxR/EGFR-IN-1 (Compound L1Au2) is a TrxR/EGFR inhibitor. TrxR/EGFR-IN-1 is active against both Gefitinib (HY-50895)-sensitive and resistant lung cancers, effectively inhibiting tumor proliferation and promoting apoptosis. TrxR/EGFR-IN-1 promotes the degradation of GPX4 protein through autophagolysosomal and proteasomal pathways, leading to ferroptosis. In addition, TrxR/EGFR-IN-1 can induce endoplasmic reticulum stress and trigger immunogenic cell death. TrxR/EGFR-IN-1 can be used for the research of Gefitinib (HY-50895)-resistant lung cancer[1].

Produkteigenschaften

• Molekulargewicht: 710.88
• CAS Nummer: [3038386-42-1]
• Formel: C24H24AuClFN6O2P
• Target-Kategorie: Apoptosis,EGFR,Ferroptosis,TrxR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound