Apoptosis inducer 30 (Compound 15a) is an anticancer agent. Apoptosis inducer 30 induces MCF-7 cells apoptosis through mitochondrial pathway. Apoptosis inducer 30 induces intracellular reactive oxygen species levels and decreases mitochondrial membrane potential, and blocks the cell cycle in the G0/G1 phase. Apoptosis inducer 30 inhibits cell growth, with an IC50 value of 0.32 µM against MCF-7 cells, and inhibits tumor growth in a mouse model of breast cancer[1].
Molekulargewicht:
882.99
Formel:
C52H69BrNO4P
Target-Kategorie:
Apoptosis,Caspase,Cytochrome P450,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten