YAP/TAZ-TEAD-IN-2 (Compound 51) is a YAP/TAZ-TEAD inhibitor that inhibits the interaction between YAP/TAZ and TEAD. YAP/TAZ-TEAD-IN-2 suppresses the transcriptional activity of TEAD, with an IC50 of 1.2 nM. YAP/TAZ-TEAD-IN-2 inhibits YAP/TAZ-TEAD target genes expression (Cyr61, CTGF, AXL and Survivin) and breast cancer cell proliferation[1].
Molekulargewicht:
356.44
Formel:
C19H20N2O3S
Target-Kategorie:
Survivin,TAM Receptor,YAP
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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