LC3B recruiter 2, CAS [[380636-64-6]]

Artikelnummer: MCE-HY-168892
Artikelname: LC3B recruiter 2, CAS [[380636-64-6]]
Artikelnummer: MCE-HY-168892
Hersteller Artikelnummer: HY-168892
Alternativnummer: MCE-HY-168892-10MG, MCE-HY-168892-50MG, MCE-HY-168892-100MG, MCE-HY-168892-5MG, MCE-HY-168892-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
LC3B recruiter 2 (34R) is an LC3B recruiter and a component of the autophagy-lysosome pathway degradation system (ATTEC, Autophagy-Tethering Compounds), which directly binds to LC3B. LC3B recruiter 2 binds to CDK9 inhibitor SNS-032 (HY-10008) through a linker, forming an ATTEC that targets the degradation of the CDK9 and Cyclin T1 complex (with inhibitory effects on both). Therefore, LC3B recruiter 2 exerts activity through the LC3B-dependent autophagy-lysosome pathway, interfering with the cell cycle of cancer cells, thus exhibiting antitumor activity[1].
Molekulargewicht: 224.64
Reinheit: 98.11
CAS Nummer: [380636-64-6]
Formel: C10H9ClN2O2
Target-Kategorie: Atg8/LC3,Autophagy
Anwendungsbeschreibung: MCE Product type: Reference compound