Apoptosis Inducer 28 (Compound X1) is an apoptosis-inducing agent with anticancer activity in vitro. Apoptosis Inducer 28 can arrest the cell cycle at the G1 phase, promote cell death, and induce apoptosis by disrupting mitochondrial membrane potential. Apoptosis inducer 28 can also decrease the production of reactive oxygen species, downregulate the gene expression of BAX, Bcl-xL, and Bcl-2, while upregulating the gene expression of PAR-4[1].
Molekulargewicht:
573.45
Formel:
C26H22Cl2N4O5S
Target-Kategorie:
Apoptosis,Bcl-2 Family,Protease Activated Receptor (PAR),Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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